Sure. Setting up a proxy is just a relay:

1. Apache (or Nginx or others) receives the request from the browser
2. The proxy decides where to send the request
3. sends a new request to internal server (e.g. http://localhost:3000/)
4. The app generates a response
5. sends the response to the Proxy (simple HTTP)
6. Proxy encrypts the response (for HTTPS)
7. Proxy sends the response to the browser

This has several advantages:

• Hides our server from the outside
• Handles HTTPS for us
• Possibly cache or compress responses
• Does logging, other stuff